Huperzine A is a substance purified from a plant called Chinese club moss.
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Huperzine A inhibits the breakdown of the neurotransmitter acetylcholine by the enzyme acetylcholinesterase. It means that it stops an enzyme from breaking down acetylcholine which results in increases in acetylcholine. Since acetylcholine has a specific role in learning and memory, Huperzine A is known as a cognitive enhancer and may be useful in fighting a cognitive decline in the elderly.
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According to some studies, taking Huperzine A by mouth for up to 8 weeks can help people with Alzheimer's disease or dementia improve their memory, mental function, and behavior. Unfortunately, there is a lack of large-scale human trials to support its efficacy and long-term safety.
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Huperzine A may lead to with mild cholinergic side effects such as nausea, vomiting, and diarrhea.
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Consult your doctor before using Huperzine A if you are currently taking any anticholinergic drugs, acetylcholinesterase inhibitors, or cholinergic drugs. In addition, Huperzine A may have additive effects if taken with drugs, such as beta-blockers.
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