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Parkinson's disease stars in the gut?


❗Parkinson's disease and gut health.

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Undoubtedly, gut health is important for brain health. In the scientific literature, we can find more evidence that Parkinson's disease (PD) begins in the gastrointestinal tract, not in the brain.

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🔹Alpha-synuclein is a protein that aggregates as amyloid fibrils in the brains of patients with Parkinson's disease and dementia with Lewy bodies. The hypothesisis that α-synuclein aggregation begins in

the gut and spreads to the central nervous system.

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🔬Research done on mice suggests that assemblies of the protein alpha-synuclein injected in the gut wall or ingested by the animals can cause a pathology that spreads to the brain.

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Most patients suffering from PD experience many digestive problems (like constipation) 10 years before motor

symptoms occur. It's important to never ignore any symptoms related to the gut, even if it's something common like constipation.

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👉Let's keep in mind that even if something is common, it doesn't mean that it's normal.

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Nowadays, scientists try to understand how gut bacteria, gut infections, and a so-called "leaky gut"might predispose people to develop PD. There may be specific microbes that make people more

susceptible to the disease. That's why it is so crucial to identify certain strains of bacteria or viruses that could help health professionals to screen for Parkinson's disease before the symptoms occur.

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🥗So far there is no specific diet that reduced the progression of PD in the clinical settings. However, following a whole-foods, a nutrient-dense diet is recommended to many patients with medical conditions. Mediterranean-DASH Intervention for Neurogenerative Delay (MIND) diet may be the best diet program for any neurodegenerative disease.

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https://doi.org/10.1016/j.parkreldis.2016.03.012

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#minddiet#dash#dashdiet#mind#research#neuroscience#neurlogy#functionalmedicine

#medicine#lewybodies#brainpathology#stroke#leakygut#gutbacteria

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